Development Partners

Continuous Manufacturing and Crystallization (CMAC) Centre of Excellence

NiTech’s technology was the inspiration for the new EPSRC-funded Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallization (CMAC). This is being led by the University of Strathclyde in Glasgow, Scotland, together with the Universities of Bath, Cambridge, Edinburgh, Glasgow, Heriot-Watt and Loughborough.

Industry Support

Provided by industry partners that include GlaxoSmithKline, AstraZeneca, Novartis, Fujifilm, Croda International plc, Genzyme Ltd and others.

NiTech technology supports CMAC to:

Enable change from batch to fully continuous manufacturing processes for high value chemical products.
Produce better chemical and pharmaceutical products, at lower cost and more sustainably through transformational change in how particles are manufactured.
Increase manufacturing competitiveness via reducing costs and enabling the creation of higher value products.

Continuous Manufacturing and
Crystallization (CMAC) papers

www.cmac.ac.uk

Centre For Process Innovation (CPI)

CPI is a technology innovation centre that works with universities, small- and medium-sized enterprises (SMEs) and multi-national businesses to help them overcome innovation challenges and bring new products and processes to market. Operating across a range of complementary technologies; formulation, biologics, printable electronics and industrial biotechnology and biorefining, CPI supports companies to help them develop, prove, prototype and scale-up next generation formulated products across a range of market sectors.

CPI is working with NiTech on the Innovate UK funded project, Flex_Manu, providing expertise in scale-up and process development using continuous oscillating baffle reactor (COBR) technology for surfactant production.

www.uk-cpi.com

La Maison Européenne Des Procédés Innovants (MEPI)

MEPI is a technology innovation platform located in Toulouse, France, promoting green chemistry on an industrial scale. MEPI has unique know-how in testing novel chemical equipment for continuous intensified processes, helping companies in the pharma, fine & specialty chemicals and cosmetic industries to implement flow chemistries, crystallizations and formulations.

MEPI has developed successfully a significant number of chemical reactions, precipitations, particle size engineering, nanoparticle and grafting generations, using NiTech’s continuous oscillatory baffled reactor (COBR). This COBR is a very efficient trouble-shooting tool to solve challenging chemical production issues. It is available at MEPI for testing your chemistries.

Download presentation from MEPI
president Laurent Pichon at the
Flow Chemistry Society Symposium
in Mumbai, India, in January 2018.
Download pdf

Download MEPI brochure

www.mepi.fr

Nalas Engineering

Nalas Engineering has engineers, scientists and analysts that are highly experienced in developing manufacturing processes for energetic materials, pharmaceuticals, and fine and specialty chemicals, including the manufacture of cGMP products.

Based in Connecticut, USA, the Nalas team offers chemistry and chemical engineering expertise to enable the development and transition of safe, sustainable, robust and lowest-cost chemical processes.

As experts in continuous processing and scale-up, the Nalas lab is equipped with a NiTech DN15 unit ready for evaluating and developing chemical processes for flow. Nalas also offers a full suite of in-situ analytical tools as well as a full analytical suite for offline chemical analysis and solid-state characterisation. Visit www.nalasengineering.com

www.nalasengineering.com

Purdue University

Purdue University is a public research university located in West Lafayette, Indiana, USA. Purdue’s Davidson School of Chemical Engineering is researching process systems, engineering approaches and tools for product design and optimal operation in the pharmaceutical, fine chemical, biotechnology, food and agrochemical industries. The university is aiming to develop theoretically founded, practical methodologies for complex processes with quantifiable performance improvements that can be supported in an industrial environment. Purdue is currently using a NiTech unit in its research.

www.purdue.edu

Relex Process Consultancy

NiTech’s agent in Israel is Relex Process Consultancy. The company, which is based in Srigim Lion, central Israel, specialises in continuous flow reactors (micro, and meso). Relex has more than 26-years’ experience in supplying process equipment and can assist customers with its own pilot-scale units or in performing trials in collaboration with NiTech.

www.relex-process.com

Research Institute of Sweden (RISE)

Research Institute of Sweden (RISE), Division Bioscience and Materials, Process and Pharmaceutical Development (RISE-PPD)

RISE can carry out feasibility studies on chemical synthesis and crystallization processes and provide a proof of concept for a continuous process. The institute is equipped with a NiTech Evaluator and a NiTech DN15 Plus unit and can provide full analytical support during development in terms of chemical analyses and solid-state characterisations.

RISE has long experience of developing processes in the pharmaceutical industry, including substance processes and pharmaceutical formulations. RISE also has a small pilot plant for manufacturing GMP and technical-quality material as well as formulated products. Visit www.sp.se

Download RISE brochure

www.ri.se/en

SAS PIVERT

SAS PIVERT, a public-private partnership established by leading French agricultural companies and supported by the French government, develops processes and proprietary products from biorefining. It is leading the GENESYS pre-competitive research programme and building/managing a modular and scalable technological platform at its BIOGIS Centre.

The MATURATION projects at BIOGIS aim to industrialise chemical products and energy from oilseed biomass. PIVERT is using a high-pressure ATEX-compliant DN15 crystalliser/reactor to support its bio-chemistry research and development work.

sas-pivert.com

Shenzhen E-Zheng

Shenzhen E-Zheng Technology Co. Ltd, based in Shenzhen, Guangdong, is NiTech’s agent in China. The company’s main products complement NiTech’s offering and include a continuous flow micro-reactor; continuous agitated cell reactor; continuous crystallizer, as well as units for continuous extraction and centrifugation, providing the ability to build integral continuous flow solutions. E-Zheng has also established collaborations with Zhejiang University of Technology and Hebei University of Technology to carry out chemical synthesis and pharmaceutical feasibility research for universities and industries.