CMAC Papers

Workflow Paper

The Cooling Crystallisation Workflow paper that is a major output of the EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation 2011-2016 has been published online in the journal Molecular Systems Design & Engineering.
Read Workflow Paper here

Agnew, Lauren R., McGlone, Thomas, Wheatcroft, Helen P., Robertson, Amy, Parsons, Anna R., & Wilson, Chick C. (2017)

Continuous Crystallization of Paracetamol (Acetaminophen) Form II: Selective Access to a Metastable Solid Form.
Crystal Growth & Design, 17(5), 2418-2427. doi:

McLachlan, Hannah, & Ni, Xiong-Wei. (2016)

On the effect of added impurity on crystal purity of urea in an oscillatory baffled crystallizer and a stirred tank crystallizer.
Journal of Crystal Growth:

Ni, Xiong-Wei, & McLachlan, Hannah. (2016)

An Investigation into Parameters Affecting Crystal Purity of Urea in a Stirred Tank and an Oscillatory Baffled Crystallizer.
Chemical Engineering Communications:

Yang, Huaiyu, Yu, Xi, Raval, Vishal, Makkawi, Yassir, & Florence, Alastair. (2016)

Effect of Oscillatory Flow on Nucleation Kinetics of Butyl Paraben.
Crystal Growth & Design:

Briggs, Naomi E. B., Schacht, Ulrich, Raval, Vishal, McGlone, Thomas, Sefcik, Jan, & Florence, Alastair J. (2015)

Seeded Crystallization of β-l-Glutamic Acid in a Continuous Oscillatory Baffled Crystallizer.
Organic Process Research & Development:

McGlone, Thomas, Briggs, Naomi, Clark, Catriona, Brown, Cameron, Sefcik, Jan, & Florence, Alastair J. (2015)

Oscillatory flow reactors (OFRs) for continuous manufacturing and crystallization.
Organic Process Research & Development:

Brown, C. J., Lee, Y. C., Nagy, Z. K., & Ni, X. (2014)

Evaluation of crystallization kinetics of adipic acid in an oscillatory baffled crystallizer.

Callahan, Craig J., & Ni, Xiong-Wei. (2014)

An investigation into the effect of mixing on the secondary nucleation of sodium chlorate in a stirred tank and an oscillatory baffled crystallizer.

Zhao, Lihua, Raval, Vishal, Briggs, Naomi E. B., Bhardwaj, Rajni M., McGlone, Thomas, Oswald, Iain D. H., & Florence, Alastair J. (2014)

From discovery to scale-up: α-lipoic acid : nicotinamide co-crystals in a continuous oscillatory baffled crystalliser.

Manninen, Mikko, Gorshkova, Elena, Immonen, Kirsi, & Ni, Xiong-Wei. (2013)

Evaluation of axial dispersion and mixing performance in oscillatory baffled reactors using CFD.
Journal of Chemical Technology & Biotechnology:

Brown, Cameron J., & Ni, Xiong-Wei. (2012)

Determination of metastable zone width, mean particle size and detectable number density using video imaging in an oscillatory baffled crystallizer.

Callahan, Craig J., & Ni, Xiong-Wei. (2012)

Probing into Nucleation Mechanisms of Cooling Crystallization of Sodium Chlorate in a Stirred Tank Crystallizer and an Oscillatory Baffled Crystallizer.
Crystal Growth & Design:

Brown, C. J.; Ni, X.-W.,

Evaluation of Growth Kinetics of Antisolvent Crystallization of Paracetamol in an Oscillatory Baffled Crystallizer Utilizing Video Imaging.
Crystal Growth & Design 2011, 11 (9), 3994-4000. doi: 10.1021/cg200560b

Brown, Cameron J., & Ni, Xiongwei. (2011)

Online Evaluation of Paracetamol Antisolvent Crystallization Growth Rate with Video Imaging in an Oscillatory Baffled Crystallizer.
Crystal Growth & Design, 11(3), 719-725. doi: 10.1021/cg1011988

Continuous Manufacturing and Crystallisation (CMAC)