Reactions

Mixing in NiTech reactors is achieved by eddy motions that are generated by the combination of fluid oscillation and the presence of baffles. It is not controlled by net flow as in other flow reactors.

This unique ability to decouple net flow from mixing accommodates longer reaction/process times, e.g. 2 hours. NiTech’s tubular baffled reactor (TBR) technology can be used for reaction times from seconds to a few minutes.

Our technologies are suitable for processes including liquid-liquid, solid-liquid, some gas-liquid, and some gas-liquid-solid processes, e.g. hydrogenation.

The pie chart below illustrates the reaction time distributions for a large number of chemicals, pharmaceuticals and food products.

 

NiTech reaction time distributions

Processes

  • Biocatalysis
  • Catalysis
  • Emulsions and Dispersions
  • Hydrogenations
  • Mixing
  • Organic Chemistry
  • Polymerisation
  • Solvent Extraction

REACTOR

Tubular baffled reactor (TBR)

PHASES

REACTIONS

Liquid-solid-gas

Carbonation

Liquid-liquid-solid

Hyaluronic acid blending/formulation

Liquid-solid

Acetylation

Liquid-liquid

Basification

Continuous oscillatory baffled reactor (COBR)

PHASES

REACTIONS

Liquid-solid-gas

Hydrogenation

Liquid-solid

Wetting
Diazotisation
Cyclisation
Drug encapsulation
Acetylation
Bromination
Enzymatic reactions
Polymer dissolution

Liquid-liquid

Polymerisation
Transesterification
Hydration of nitrile amide
Boronation
Nitration

Liquid-gas

Oxidation
Hydroformylation

Liquid-liquid separation

In-line phase separation